Analysis of the functional activity of plants with known antibacterial and neurotropic properties
Abstract
The degree of biological activity of aqueous and alcoholic extracts of medicinal plants on strains of Staphylococcus aureus and Escherichia coli was assessed. The raw materials of medicinal plants from the pharmacy network and growing in natural plant communities of the North Caucasus (mountainous regions of the Republic of North Ossetia-Alania, Upper Tsey gorge) were used. The degree of antibacterial activity of the tested substances was determined by the standardized Kerby-Bauer method. High antibacterial activity of extracts of common thyme, common garlic, coltsfoot and rod-shaped eucalyptus against Staphylococcus aureus was established. The Escherichia coli culture turned out to be resistant to almost all tested substances (no growth retardation, or low sensitivity). The results of the comparative analysis of the antibacterial activity of the tested medicinal plants revealed more significant biological activity of raw materials of medicinal plants from natural plant communities of the North Caucasus.
About the Authors
Z. G. Khabaeva
Северо-Осетинский государственный университет им. К.Л. Хетагурова
Russian Federation
Russian Federation
V. S. Gappoeva
Северо-Осетинский государственный университет им. К.Л. Хетагурова
Russian Federation
Russian Federation
D. A. Marzoeva
Северо-Осетинский государственный университет им. К.Л. Хетагурова
Russian Federation
Russian Federation
A. Ch. Chiviev
Северо-Осетинская государственная медицинская академия
Russian Federation
Russian Federation
I. V. Bugulova
Северо-Осетинский государственный университет им. К.Л. Хетагурова
Russian Federation
Russian Federation
References
1. Бзыков О.Р., Марзоева З.Р., Хабаева З.Г., Гаппоева В.С., Оказова З.П., Скупневский С.В. Поведенческие реакции крыс в условиях воздействия отрицательных аэроионов с использованием различных поведенческих моделей // Siberian Journal of Life Sciences and Agriculture. – 2022. – Т. 14. – No. 6. – С. 92-106. DOI: 10.12731/2658-6649-2022-14-6-92-106
2. Самбукова Т.В., Овчинников Б.В., Ганапольский В.П., и др. Перспективы использования фитопрепаратов в современной фармакологии // Обзоры по клинической фармакологии и лекарственной терапии. – 2017. – Т. 15. – № 2. – С. 56-63. DOI: 10.17816/RCF15256-63
3. Хабаева З.Г., Гаппоева В.С., Чивиев А.Ч. Исследование функциональной активности мелиссы лекарственной (Melissa officinalis L.) с использованием поведенческих моделей // Научно-теоретический журнал Известия Горского государственного аграрного университета. – 2022. – № 4 (59). DOI: 10.54258/20701047_2022_59_4_207
4. Щербакова И.В., Крылатых В.Ю., Барденштейн Л.М. Психофармакотерапия тревожных расстройств: современный взгляд на проблему // Российский медицинский журнал. – 2017. – Вып. 23. № 2. – С.107-112.
5. Abubakar AR, Haque M. Preparation of Medicinal Plants: Basic Extraction and Fractionation Procedures for Experimental Purposes // J Pharm Bioallied Sci. – 2020. – Vol. 12. – № 1. – P. 1-10. DOI: 10.4103/jpbs.JPBS_175_19. Epub 2020 Jan 29. PMID: 32801594; PMCID: PMC7398001.
6. Bykov Yu.V., Bekker R.A. History of the development of anxiolytics (A Literature Review) // Psychiatry and psychopharmacotherapy. – 2023. – Vol 3. – P. 16-32.
7. Gappoeva V., Khabayeva Z., Gagloeva A.R., Agayeva F., Bugulova I. Features of the functional activity of Melissa officinalis (Melissa officinalis L.) and medicinal mixture based on it // BIO Web of Conferences. International Scientific and Practical Conference “VAVILOV READINGS-2023” (VVRD 2023). – 2023. – Vol. 67. – P. 01011.
8. Kim S.H, Lim J.H. Traditional East Asian Herbal Medicine for Post-Stroke Insomnia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials // Int J Environ Res Public Health. – 2022. – Vol. 3. – № 19(3). – Р. 1754. DOI: 10.3390/ijerph19031754. PMID: 35162777; PMCID: PMC8834856.
9. Nascimento G.F., Locatelli J, Freitas P.C., Silva G.L. Antimicrobial activity of plants on antibiotic resistance bacteria // Braz. J. Microbiol. – 2000. – Vol. 3. – P. 115-120
10. Sakkas H., Papadopoulou C. Antimicrobial activity of basil, oregano, and thyme essential oils // J. Microbiol. Biotechnol. – 2017. – Vol. 27. – № 3. – Р. 429-438.
11. Sarris J., Panossian A., Schweitzer I., Stough C., Scholey A. Herbal medicine for depression, anxiety and insomnia: a review of psychopharmacology and clinical evidence // Eur Neuropsychopharmacol. – 2011. – Vol. 21. – № 12. – P. 841-60. DOI: 10.1016/j.euroneuro.2011.04.002. Epub 2011 May 23. PMID: 21601431.
12. Woo C. S. J., Han Lau J. S., El-Nezami H. Chapter 10. Herbal Medicine: Toxicity and Recent Trends in Assessing Their Potential Toxic Effects // Advances in Botanical Research. – 2012. – Vol. 62. – P. 365-384.
Review
For citations:
Khabaeva Z.G., Gappoeva V.S., Marzoeva D.A., Chiviev A.Ch., Bugulova I.V. Analysis of the functional activity of plants with known antibacterial and neurotropic properties. Bulletin of the State Nikitsky Botanical Gardens. 2024;(152):134-140. (In Russ.)
Views:
77
Email this article 